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Promises and challenges in pharmacoepigenetics

Pharmacogenetics, the study of how interindividual genetic differences affect drug response, does not explain all observed heritable variance in drug response. Epigenetic mechanisms, such as DNA methylation, and histone acetylation may account for some of the unexplained variances. Epigenetic mechan...

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Detalles Bibliográficos
Autores principales: Smith, Delaney A., Sadler, Marie C., Altman, Russ B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406571/
https://www.ncbi.nlm.nih.gov/pubmed/37560024
http://dx.doi.org/10.1017/pcm.2023.6