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Improved Pathologic response to chemoradiation in MGMT methylated locally advanced rectal cancer

BACKGROUND AND PURPOSE: With the growing interest in total neoadjuvant treatment for locally advanced rectal adenocarcinoma (LARC) there is an urgent unmet need to identify predictive markers of response to long-course neoadjuvant concurrent chemoradiotherapy (LCRT). O6-Methylguanine (O6-MG)-DNA-met...

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Detalles Bibliográficos
Autores principales: Jensen, Garrett L., Pourfarrokh, Niloufar, Volz, Marcus, Morales, Linden L., Walker, Kimberly, Hammonds, Kendall P., El-Ghamry, Moataz, Wong, Lucas, Hodjat, Parsa, Castro, Eduardo, Rao, Arundhati, Jhavar, Sameer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406619/
https://www.ncbi.nlm.nih.gov/pubmed/37560324
http://dx.doi.org/10.1016/j.ctro.2023.100667