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Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga

Much is known about the generation, removal, and roles of 5-methylcytosine (5mC) in eukaryote DNA, and there is a growing body of evidence regarding N6-methyladenine, but very little is known about N4-methylcytosine (4mC) in the DNA of eukaryotes. The gene for the first metazoan DNA methyltransferas...

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Detalles Bibliográficos
Autores principales: Zhou, Jujun, Horton, John R., Kaur, Gundeep, Chen, Qin, Li, Xuwen, Mendoza, Fabian, Wu, Tao, Blumenthal, Robert M., Zhang, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406627/
https://www.ncbi.nlm.nih.gov/pubmed/37414145
http://dx.doi.org/10.1016/j.jbc.2023.105017