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Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells

Cervical cancer is one of the leading causes of cancer death in women. Mitochondrial-mediated ferroptosis (MMF) is a recently discovered form of cancer cell death. However, the role and the underlying mechanism of MMF in cervical cancer remain elusive. Here, using an unbiased screening for mitochond...

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Detalles Bibliográficos
Autores principales: Wang, Xuan, Ji, Yuting, Qi, Jingyi, Zhou, Shuaishuai, Wan, Sitong, Fan, Chang, Gu, Zhenglong, An, Peng, Luo, Yongting, Luo, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406804/
https://www.ncbi.nlm.nih.gov/pubmed/37550282
http://dx.doi.org/10.1038/s41419-023-06033-2