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Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens

The dosage of colistin for the treatment of enteric E. coli in animals necessitates considering the heteroresistant (HR) nature of the targeted inoculum, described by the presence of a major susceptible population (S1, representing 99.95% of total population) mixed with an initial minor subpopulatio...

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Detalles Bibliográficos
Autores principales: Mead, Andrew, Toutain, Pierre-Louis, Richez, Pascal, Pelligand, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406827/
https://www.ncbi.nlm.nih.gov/pubmed/37550398
http://dx.doi.org/10.1038/s41598-023-39727-w