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Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis

The role of iron in the two major sites of adaptive thermogenesis, namely the beige inguinal (iWAT) and brown adipose tissues (BAT) has not been fully understood yet. Body iron levels and distribution is controlled by the iron regulatory peptide hepcidin. Here, we explored iron homeostasis and therm...

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Detalles Bibliográficos
Autores principales: Deschemin, Jean-Christophe, Ransy, Céline, Bouillaud, Frédéric, Chung, Soonkyu, Galy, Bruno, Peyssonnaux, Carole, Vaulont, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406828/
https://www.ncbi.nlm.nih.gov/pubmed/37550331
http://dx.doi.org/10.1038/s41598-023-39305-0