Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing

Chronic wounds impose a significant healthcare burden to a broad patient population. Cell-based therapies, while having shown benefits for the treatment of chronic wounds, have not yet achieved widespread adoption into clinical practice. We developed a CRISPR/Cas9 approach to precisely edit murine d...

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Detalles Bibliográficos
Autores principales: Henn, Dominic, Zhao, Dehua, Sivaraj, Dharshan, Trotsyuk, Artem, Bonham, Clark Andrew, Fischer, Katharina S., Kehl, Tim, Fehlmann, Tobias, Greco, Autumn H., Kussie, Hudson C., Moortgat Illouz, Sylvia E., Padmanabhan, Jagannath, Barrera, Janos A., Kneser, Ulrich, Lenhof, Hans-Peter, Januszyk, Michael, Levi, Benjamin, Keller, Andreas, Longaker, Michael T., Chen, Kellen, Qi, Lei S., Gurtner, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406832/
https://www.ncbi.nlm.nih.gov/pubmed/37550295
http://dx.doi.org/10.1038/s41467-023-40519-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406832/
https://www.ncbi.nlm.nih.gov/pubmed/37550295
http://dx.doi.org/10.1038/s41467-023-40519-z

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