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Getting personal with epigenetics: towards individual-specific epigenomic imputation with machine learning

Epigenetic modifications are dynamic mechanisms involved in the regulation of gene expression. Unlike the DNA sequence, epigenetic patterns vary not only between individuals, but also between different cell types within an individual. Environmental factors, somatic mutations and ageing contribute to...

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Detalles Bibliográficos
Autores principales: Hawkins-Hooker, Alex, Visonà, Giovanni, Narendra, Tanmayee, Rojas-Carulla, Mateo, Schölkopf, Bernhard, Schweikert, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406842/
https://www.ncbi.nlm.nih.gov/pubmed/37550323
http://dx.doi.org/10.1038/s41467-023-40211-2