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Getting personal with epigenetics: towards individual-specific epigenomic imputation with machine learning
Epigenetic modifications are dynamic mechanisms involved in the regulation of gene expression. Unlike the DNA sequence, epigenetic patterns vary not only between individuals, but also between different cell types within an individual. Environmental factors, somatic mutations and ageing contribute to...
Autores principales: | Hawkins-Hooker, Alex, Visonà, Giovanni, Narendra, Tanmayee, Rojas-Carulla, Mateo, Schölkopf, Bernhard, Schweikert, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406842/ https://www.ncbi.nlm.nih.gov/pubmed/37550323 http://dx.doi.org/10.1038/s41467-023-40211-2 |
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