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Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles

Extracellular vesicles (EVs) are gaining ground as next-generation drug delivery modalities. Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability represents a robust cargo loading strategy. To address the paucity of such scaffold proteins, we leverage a simple...

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Detalles Bibliográficos
Autores principales: Zheng, Wenyi, Rädler, Julia, Sork, Helena, Niu, Zheyu, Roudi, Samantha, Bost, Jeremy P., Görgens, André, Zhao, Ying, Mamand, Doste R., Liang, Xiuming, Wiklander, Oscar P. B., Lehto, Taavi, Gupta, Dhanu, Nordin, Joel Z., EL Andaloussi, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406850/
https://www.ncbi.nlm.nih.gov/pubmed/37550290
http://dx.doi.org/10.1038/s41467-023-40453-0