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Development and evaluation of febuxostat solid dispersion through screening method

Febuxostat (Febux) is a BCS II drug and has a very low solubility. In order to overcome this shortcoming, the purpose of study is to increase the in vitro dissolution (%) and drug release (%) of Febux by using a screening method. The Febux-SD formulation was prepared by screening solubilizers, pH ag...

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Detalles Bibliográficos
Autores principales: Sohn, Jeong Sun, Choi, Jin-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406859/
https://www.ncbi.nlm.nih.gov/pubmed/37559865
http://dx.doi.org/10.1016/j.jsps.2023.101724