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Spontaneous histone exchange between nucleosomes

The nucleosome is the fundamental gene-packing unit in eukaryotes. Nucleosomes comprise ∼147 bp DNA wrapped around an octameric histone protein core composed of two H2A-H2B dimers and one (H3-H4)(2) tetramer. The strong yet flexible DNA–histone interactions are the physical basis of the dynamic regu...

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Detalles Bibliográficos
Autores principales: Das, Subhra Kanti, Huynh, Mai Thao, Lee, Tae-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406861/
https://www.ncbi.nlm.nih.gov/pubmed/37442235
http://dx.doi.org/10.1016/j.jbc.2023.105037