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ISL1 regulates lung branching morphogenesis via Shh signaling pathway

Lung branching morphogenesis relies on a complex coordination of multiple signaling pathways and transcription factors. Here, we found that ablation of the LIM homeodomain transcription factor Islet1 (Isl1) in lung epithelium resulted in defective branching morphogenesis and incomplete formation of...

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Detalles Bibliográficos
Autores principales: Huang, Ruiqi, Zhang, Chujing, Zheng, Yuting, Zhang, Wei, Huang, Huarong, Qiu, Mengsheng, Li, Jianying, Li, Feixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406864/
https://www.ncbi.nlm.nih.gov/pubmed/37442233
http://dx.doi.org/10.1016/j.jbc.2023.105034