Effects of metformin and donepezil on the prevention of doxorubicin-induced cardiotoxicity in breast cancer: a randomized controlled trial

Doxorubicin (DOX) causes deleterious cardiotoxicity. We aimed to investigate the protective roles of metformin and donepezil against DOX-induced cardiotoxicity. In this randomized-controlled trial, 143 female breast cancer patients were enrolled. Metformin (n = 43), donepezil (n = 52), or placebo (n...

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Detalles Bibliográficos
Autores principales: Osataphan, Nichanan, Phrommintikul, Arintaya, Leemasawat, Krit, Somwangprasert, Areewan, Apaijai, Nattayaporn, Suksai, Supanai, Sirikul, Wachiranun, Gunaparn, Siriluck, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406870/
https://www.ncbi.nlm.nih.gov/pubmed/37550350
http://dx.doi.org/10.1038/s41598-023-40061-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406870/
https://www.ncbi.nlm.nih.gov/pubmed/37550350
http://dx.doi.org/10.1038/s41598-023-40061-4

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