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Imaging-based study demonstrates how the DEK nanoscale distribution differentially correlates with epigenetic marks in a breast cancer model

Epigenetic dysregulation of chromatin is one of the hallmarks of cancer development and progression, and it is continuously investigated as a potential general bio-marker of this complex disease. One of the nuclear factors involved in gene regulation is the unique DEK protein—a histone chaperon modu...

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Detalles Bibliográficos
Autores principales: Pierzynska-Mach, Agnieszka, Cainero, Isotta, Oneto, Michele, Ferrando-May, Elisa, Lanzanò, Luca, Diaspro, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406876/
https://www.ncbi.nlm.nih.gov/pubmed/37550322
http://dx.doi.org/10.1038/s41598-023-38685-7