Cargando…
Imaging-based study demonstrates how the DEK nanoscale distribution differentially correlates with epigenetic marks in a breast cancer model
Epigenetic dysregulation of chromatin is one of the hallmarks of cancer development and progression, and it is continuously investigated as a potential general bio-marker of this complex disease. One of the nuclear factors involved in gene regulation is the unique DEK protein—a histone chaperon modu...
Autores principales: | Pierzynska-Mach, Agnieszka, Cainero, Isotta, Oneto, Michele, Ferrando-May, Elisa, Lanzanò, Luca, Diaspro, Alberto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406876/ https://www.ncbi.nlm.nih.gov/pubmed/37550322 http://dx.doi.org/10.1038/s41598-023-38685-7 |
Ejemplares similares
-
Super-resolution microscopy reveals the nanoscale cluster architecture of the DEK protein cancer biomarker
por: Pierzynska-Mach, Agnieszka, et al.
Publicado: (2023) -
Nanoscale Distribution of Nuclear Sites by Super-Resolved Image Cross-Correlation Spectroscopy
por: Oneto, Michele, et al.
Publicado: (2019) -
The oncoprotein DEK affects the outcome of PARP1/2 inhibition during mild replication stress
por: Ganz, Magdalena, et al.
Publicado: (2019) -
Measuring Nanoscale Distances by Structured Illumination Microscopy and Image Cross-Correlation Spectroscopy (SIM-ICCS)
por: Cainero, Isotta, et al.
Publicado: (2021) -
Chromatin investigation in the nucleus using a phasor approach to structured illumination microscopy
por: Cainero, Isotta, et al.
Publicado: (2021)