Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) remains a highly fatal malignancy partially due to the acquired alterations related to aberrant protein glycosylation that pathologically remodel molecular biological processes and protect PDAC cells from death. Ferroptosis driven by lethal lipid peroxidation...

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Detalles Bibliográficos
Autores principales: Ma, Heng, Chen, Xianlong, Mo, Shengwei, Zhang, Yue, Mao, Xinxin, Chen, Jingci, Liu, Yilin, Tong, Wei-Min, Lu, Zhaohui, Yu, Shuangni, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406883/
https://www.ncbi.nlm.nih.gov/pubmed/37479744
http://dx.doi.org/10.1038/s41418-023-01188-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406883/
https://www.ncbi.nlm.nih.gov/pubmed/37479744
http://dx.doi.org/10.1038/s41418-023-01188-z

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