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Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains a highly fatal malignancy partially due to the acquired alterations related to aberrant protein glycosylation that pathologically remodel molecular biological processes and protect PDAC cells from death. Ferroptosis driven by lethal lipid peroxidation...
Autores principales: | Ma, Heng, Chen, Xianlong, Mo, Shengwei, Zhang, Yue, Mao, Xinxin, Chen, Jingci, Liu, Yilin, Tong, Wei-Min, Lu, Zhaohui, Yu, Shuangni, Chen, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406883/ https://www.ncbi.nlm.nih.gov/pubmed/37479744 http://dx.doi.org/10.1038/s41418-023-01188-z |
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