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Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions
The mitochondrial permeability transition (mPT) describes a Ca(2+)-dependent and cyclophilin D (CypD)-facilitated increase of inner mitochondrial membrane permeability that allows diffusion of molecules up to 1.5 kDa in size. It is mediated by a non-selective channel, the mitochondrial permeability...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406888/ https://www.ncbi.nlm.nih.gov/pubmed/37460667 http://dx.doi.org/10.1038/s41418-023-01187-0 |