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IL-1β is involved in docetaxel chemoresistance by regulating the formation of polyploid giant cancer cells in non-small cell lung cancer

Docetaxel (Doc) is a cornerstone of chemotherapy; however, treatment with Doc often and inevitably leads to drug resistance and the formation of polyploid giant cancer cells (PGCCs). In this study, we investigated the effect of Doc on non-small cell lung cancer to explore the role of PGCCs in drug r...

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Detalles Bibliográficos
Autores principales: Zhao, Song, Xing, Sining, Wang, Lili, Ouyang, Mingyue, Liu, Shuo, Sun, Lingyan, Yu, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406903/
https://www.ncbi.nlm.nih.gov/pubmed/37550397
http://dx.doi.org/10.1038/s41598-023-39880-2