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Downregulation of PIK3IP1 in retinal microglia promotes retinal pathological neovascularization via PI3K-AKT pathway activation

Retinal pathological neovascularization involves endothelial cells, pericytes, photoreceptor cells, ganglion cells, and glial cells, whose roles remain unclear. Using the Scissor algorithm, we found that microglia are associated with formation of fibrovascular membranes and can promote pathological...

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Detalles Bibliográficos
Autores principales: Chen, Lushu, Cao, Yuan, Shen, Yaming, Li, Huan, Ye, Rong, Yao, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406944/
https://www.ncbi.nlm.nih.gov/pubmed/37550343
http://dx.doi.org/10.1038/s41598-023-39473-z