Rational design of oral drugs targeting mucosa delivery with gut organoid platforms

Effective oral drugs and vaccines require high delivery efficiency across the gastrointestinal epithelia and protection of medically effective payloads (i.e., immunogens) against gastric damage. In this study, hollowed nanocarriers (NCs: silica nanospheres and gold nanocages) with poly-l-lysine (PLL...

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Detalles Bibliográficos
Autores principales: Tong, Tianjian, Qi, Yijun, Rollins, Derrick, Bussiere, Luke D., Dhar, Debarpan, Miller, Cathy L., Yu, Chenxu, Wang, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406959/
https://www.ncbi.nlm.nih.gov/pubmed/37560199
http://dx.doi.org/10.1016/j.bioactmat.2023.07.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406959/
https://www.ncbi.nlm.nih.gov/pubmed/37560199
http://dx.doi.org/10.1016/j.bioactmat.2023.07.014

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