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Rational design of oral drugs targeting mucosa delivery with gut organoid platforms
Effective oral drugs and vaccines require high delivery efficiency across the gastrointestinal epithelia and protection of medically effective payloads (i.e., immunogens) against gastric damage. In this study, hollowed nanocarriers (NCs: silica nanospheres and gold nanocages) with poly-l-lysine (PLL...
Autores principales: | Tong, Tianjian, Qi, Yijun, Rollins, Derrick, Bussiere, Luke D., Dhar, Debarpan, Miller, Cathy L., Yu, Chenxu, Wang, Qun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406959/ https://www.ncbi.nlm.nih.gov/pubmed/37560199 http://dx.doi.org/10.1016/j.bioactmat.2023.07.014 |
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