PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

Retinosomes are intracellular lipid bodies found in the retinal pigment epithelium (RPE). They contain retinyl esters (REs) and are thought to be involved in visual chromophore regeneration during dark adaptation and in case of chromophore depletion. However, key enzymes in chromophore regeneration,...

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Detalles Bibliográficos
Autores principales: Hara, Miwa, Wu, Wenjing, Malechka, Volha V., Takahashi, Yusuke, Ma, Jian-Xing, Moiseyev, Gennadiy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406976/
https://www.ncbi.nlm.nih.gov/pubmed/36763501
http://dx.doi.org/10.1016/j.celrep.2023.112091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406976/
https://www.ncbi.nlm.nih.gov/pubmed/36763501
http://dx.doi.org/10.1016/j.celrep.2023.112091

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