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HDAC inhibitor attenuates rat traumatic brain injury induced neurological impairments

Oxidative stress plays an important role in the secondary neuronal damage after traumatic brain injury (TBI). Inhibition of histone deacetylases (HDACs) has been shown to reduce reactive oxygen species (ROS) production and NADPH oxidases (Nox) transcription. Vorinostat is an HDAC inhibitor. This stu...

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Detalles Bibliográficos
Autores principales: Lu, Yiming, Chen, Yiming, Xu, Siyi, Wei, Liang, Zhang, Yanfei, Chen, Wei, Liu, Min, Zhong, Chunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407045/
https://www.ncbi.nlm.nih.gov/pubmed/37560709
http://dx.doi.org/10.1016/j.heliyon.2023.e18485