The cytoplasmic fraction of the histone lysine methyltransferase Setdb1 is essential for embryonic stem cells

The major lysine methyltransferase (KMT) Setdb1 is essential for self-renewal and viability of mouse embryonic stem cells (mESCs). Setdb1 was primarily known to methylate the lysine 9 of histone 3 (H3K9) in the nucleus, where it regulates chromatin functions. However, Setdb1 is also massively locali...

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Detalles Bibliográficos
Autores principales: Rapone, Roberta, Del Maestro, Laurence, Bouyioukos, Costas, Albini, Sonia, Cruz-Tapias, Paola, Joliot, Véronique, Cosson, Bertrand, Ait-Si-Ali, Slimane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407132/
https://www.ncbi.nlm.nih.gov/pubmed/37559904
http://dx.doi.org/10.1016/j.isci.2023.107386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407132/
https://www.ncbi.nlm.nih.gov/pubmed/37559904
http://dx.doi.org/10.1016/j.isci.2023.107386

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