JAK/STAT blockade reverses the malignant phenotype of Hodgkin and Reed-Sternberg cells

Constitutive activation of the JAK/STAT pathway is a common phenomenon in classic Hodgkin lymphoma (cHL). The clinical potential of anti-JAK/STAT therapy is being explored in early-stage clinical trials. Notwithstanding, very little information is available about the complex biological consequences...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernández, Sara, Solórzano, Jose L., Díaz, Eva, Menéndez, Victoria, Maestre, Lorena, Palacios, Sara, López, Mar, Colmenero, Argentina, Estévez, Mónica, Montalbán, Carlos, Martínez, Ángel, Roncador, Giovanna, García, Juan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407154/
https://www.ncbi.nlm.nih.gov/pubmed/36459489
http://dx.doi.org/10.1182/bloodadvances.2021006336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407154/
https://www.ncbi.nlm.nih.gov/pubmed/36459489
http://dx.doi.org/10.1182/bloodadvances.2021006336

Ejemplares similares