The kynurenine pathway of tryptophan metabolism: a neglected therapeutic target of COVID-19 pathophysiology and immunotherapy

SARS-CoV-2 (COVID-19) exerts profound changes in the kynurenine (Kyn) pathway (KP) of tryptophan (Trp) metabolism that may underpin its pathophysiology. The KP is the main source of the vital cellular effector NAD(+) and intermediate metabolites that modulate immune and neuronal functions. Trp metab...

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Detalles Bibliográficos
Autor principal: Badawy, Abdulla Abu-Bakr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Immunology & Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407158/
https://www.ncbi.nlm.nih.gov/pubmed/37486805
http://dx.doi.org/10.1042/BSR20230595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407158/
https://www.ncbi.nlm.nih.gov/pubmed/37486805
http://dx.doi.org/10.1042/BSR20230595

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