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Deep learning‐based identification of sinoatrial node‐like pacemaker cells from SHOX2/HCN4 double‐positive cells differentiated from human iPS cells

BACKGROUND: Cardiomyocytes derived from human iPS cells (hiPSCs) include cells showing SAN‐ and non‐SAN‐type spontaneous APs. OBJECTIVES: To examine whether the deep learning technology could identify hiPSC‐derived SAN‐like cells showing SAN‐type‐APs by their shape. METHODS: We acquired phase‐contra...

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Detalles Bibliográficos
Autores principales: Wakimizu, Takayuki, Naito, Junpei, Ishida, Manabu, Kurata, Yasutaka, Tsuneto, Motokazu, Shirayoshi, Yasuaki, Hisatome, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407170/
https://www.ncbi.nlm.nih.gov/pubmed/37560272
http://dx.doi.org/10.1002/joa3.12883