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Targeting N-cadherin (CDH2) and the malignant bone marrow microenvironment in acute leukaemia

This review discusses current research on acute paediatric leukaemia, the leukaemic bone marrow (BM) microenvironment and recently discovered therapeutic opportunities to target leukaemia–niche interactions. The tumour microenvironment plays an integral role in conferring treatment resistance to leu...

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Detalles Bibliográficos
Autores principales: Parker, Jessica, Hockney, Sean, Blaschuk, Orest W., Pal, Deepali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407222/
https://www.ncbi.nlm.nih.gov/pubmed/37132370
http://dx.doi.org/10.1017/erm.2023.13