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Targeting N-cadherin (CDH2) and the malignant bone marrow microenvironment in acute leukaemia
This review discusses current research on acute paediatric leukaemia, the leukaemic bone marrow (BM) microenvironment and recently discovered therapeutic opportunities to target leukaemia–niche interactions. The tumour microenvironment plays an integral role in conferring treatment resistance to leu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407222/ https://www.ncbi.nlm.nih.gov/pubmed/37132370 http://dx.doi.org/10.1017/erm.2023.13 |