Neofunctionalization of S-adenosylmethionine decarboxylase into pyruvoyl-dependent L-ornithine and L-arginine decarboxylases is widespread in bacteria and archaea

S-adenosylmethionine decarboxylase (AdoMetDC/SpeD) is a key polyamine biosynthetic enzyme required for conversion of putrescine to spermidine. Autocatalytic self-processing of the AdoMetDC/SpeD proenzyme generates a pyruvoyl cofactor from an internal serine. Recently, we discovered that diverse bact...

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Detalles Bibliográficos
Autores principales: Li, Bin, Liang, Jue, Phillips, Margaret A., Michael, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407285/
https://www.ncbi.nlm.nih.gov/pubmed/37399976
http://dx.doi.org/10.1016/j.jbc.2023.105005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407285/
https://www.ncbi.nlm.nih.gov/pubmed/37399976
http://dx.doi.org/10.1016/j.jbc.2023.105005

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