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Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease

INTRODUCTION: There is an urgent need to determine the safety, effectiveness and cost-effectiveness of novel antiviral treatments for COVID-19 in vaccinated patients in the community at increased risk of morbidity and mortality from COVID-19. METHODS AND ANALYSIS: PANORAMIC is a UK-wide, open-label,...

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Detalles Bibliográficos
Autores principales: Gbinigie, Oghenekome, Ogburn, Emma, Allen, Julie, Dorward, Jienchi, Dobson, Melissa, Madden, Tracie-Ann, Yu, Ly-Mee, Lowe, David M, Rahman, Najib, Petrou, Stavros, Richards, Duncan, Hood, Kerenza, Patel, Mahendra, Saville, Benjamin R, Marion, Joe, Holmes, Jane, Png, May Ee, Hayward, Gail, Lown, Mark, Harris, Victoria, Jani, Bhautesh, Hart, Nigel, Khoo, Saye, Rutter, Heather, Chalk, Jem, Standing, Joseph F, Breuer, Judith, Lavallee, Layla, Hadley, Elizabeth, Cureton, Lucy, Benysek, Magdalena, Andersson, Monique I, Francis, Nick, Thomas, Nicholas P B, Evans, Philip, van Hecke, Oliver, Koshkouei, Mona, Coates, Maria, Barrett, Sarah, Bateman, Clare, Davies, Jennifer, Raymundo-Wood, Ivy, Ustianowski, Andrew, Nguyen-Van-Tam, Jonathan, Carson-Stevens, Andrew, Hobbs, Richard, Little, Paul, Butler, Christopher C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407406/
https://www.ncbi.nlm.nih.gov/pubmed/37550022
http://dx.doi.org/10.1136/bmjopen-2022-069176