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REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice

Increasing evidence supports a role for inflammation in the early development and progression of retinal complications caused by diabetes. We recently demonstrated that the stress response protein regulated in development and DNA damage response 1 (REDD1) promotes diabetes-induced retinal inflammati...

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Detalles Bibliográficos
Autores principales: Sunilkumar, Siddharth, VanCleave, Ashley M., McCurry, Christopher M., Toro, Allyson L., Stevens, Shaunaci A., Kimball, Scot R., Dennis, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407432/
https://www.ncbi.nlm.nih.gov/pubmed/37392853
http://dx.doi.org/10.1016/j.jbc.2023.104991