A luminescence-based method to assess antigen presentation and antigen-specific T cell responses for in vitro screening of immunomodulatory checkpoints and therapeutics

Investigations into the strength of antigen-specific responses in vitro is becoming increasingly relevant for decision making in early-phase research of novel immunotherapeutic approaches, including adoptive cell but also immune checkpoint inhibitor (ICI)-based therapies. In the latter, antigen-spec...

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Detalles Bibliográficos
Autores principales: Álvarez Freile, Jimena, Qi, Yuzhu, Jacob, Lisa, Lobo, Maria Franceskin, Lourens, Harm Jan, Huls, Gerwin, Bremer, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407562/
https://www.ncbi.nlm.nih.gov/pubmed/37559730
http://dx.doi.org/10.3389/fimmu.2023.1233113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407562/
https://www.ncbi.nlm.nih.gov/pubmed/37559730
http://dx.doi.org/10.3389/fimmu.2023.1233113

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