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A simple geometrical model of the electrostatic environment around the catalytic center of the ribosome and its significance for the elongation cycle kinetics

The central function of the large subunit of the ribosome is to catalyze peptide bond formation. This biochemical reaction is conducted at the peptidyl transferase center (PTC). Experimental evidence shows that the catalytic activity is affected by the electrostatic environment around the peptidyl t...

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Detalles Bibliográficos
Autores principales: Joiret, Marc, Kerff, Frederic, Rapino, Francesca, Close, Pierre, Geris, Liesbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407619/
https://www.ncbi.nlm.nih.gov/pubmed/37560126
http://dx.doi.org/10.1016/j.csbj.2023.07.016