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Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival Bcl-2 family proteins
The apoptotic pathway is regulated by protein-protein interactions between members of the Bcl-2 family. Pro-survival Bcl-2 family proteins act as cell guardians and protect cells against death. Selective binding and neutralization of BH3-only proteins with pro-survival Bcl-2 family proteins is criti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407628/ https://www.ncbi.nlm.nih.gov/pubmed/37560128 http://dx.doi.org/10.1016/j.csbj.2023.07.017 |