Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival Bcl-2 family proteins

The apoptotic pathway is regulated by protein-protein interactions between members of the Bcl-2 family. Pro-survival Bcl-2 family proteins act as cell guardians and protect cells against death. Selective binding and neutralization of BH3-only proteins with pro-survival Bcl-2 family proteins is criti...

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Detalles Bibliográficos
Autores principales: Wang, Haolan, Guo, Ming, Wei, Hudie, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407628/
https://www.ncbi.nlm.nih.gov/pubmed/37560128
http://dx.doi.org/10.1016/j.csbj.2023.07.017

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