Genetic variations in HMGCR and PCSK9 and kidney function: a Mendelian randomization study

BACKGROUND: The genetically predicted lipid-lowering effect of HMGCR or PCSK9 variant can be used to assess drug proxy effects on kidney function. METHODS: Mendelian randomization (MR) analysis-identified HMGCR and PCSK9 genetic variants were used to predict the low-density lipoprotein (LDL) cholest...

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Detalles Bibliográficos
Autores principales: Park, Sehoon, Kim, Seong Geun, Lee, Soojin, Kim, Yaerim, Cho, Semin, Kim, Kwangsoo, Kim, Yong Chul, Han, Seung Seok, Lee, Hajeong, Lee, Jung Pyo, Joo, Kwon Wook, Lim, Chun Soo, Kim, Yon Su, Kim, Dong Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Nephrology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407636/
https://www.ncbi.nlm.nih.gov/pubmed/37448291
http://dx.doi.org/10.23876/j.krcp.22.237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407636/
https://www.ncbi.nlm.nih.gov/pubmed/37448291
http://dx.doi.org/10.23876/j.krcp.22.237

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