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Paternal developmental thyrotoxicosis disrupts neonatal leptin leading to increased adiposity and altered physiology of the melanocortin system
BACKGROUND: The genetic code does not fully explain individual variability and inheritance of susceptibility to endocrine conditions, suggesting the contribution of epigenetic factors acting across generations. METHODS: We used a mouse model of developmental thyrotoxicosis (Dio3-/- mouse) to analyze...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407661/ https://www.ncbi.nlm.nih.gov/pubmed/37560296 http://dx.doi.org/10.3389/fendo.2023.1210414 |