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5-Aminolevulinic acid bypasses mitochondrial complex I deficiency and corrects physiological dysfunctions in Drosophila

Complex I (CI) deficiency in mitochondrial oxidative phosphorylation (OXPHOS) is the most common cause of mitochondrial diseases, and limited evidence-based treatment options exist. Although CI provides the most electrons to OXPHOS, complex II (CII) is another entry point of electrons. Enhancement o...

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Detalles Bibliográficos
Autores principales: Nozawa, Naoko, Noguchi, Marie, Shinno, Kanako, Saito, Taro, Asada, Akiko, Ishii, Takuya, Takahashi, Kiwamu, Ishizuka, Masahiro, Ando, Kanae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407699/
https://www.ncbi.nlm.nih.gov/pubmed/37364055
http://dx.doi.org/10.1093/hmg/ddad092