Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration

β-propellers that bind polyphosphoinositides (PROPPINs) are an autophagy-related protein family conserved throughout eukaryotes. The PROPPIN family includes Atg18, Atg21 and Hsv2 in yeast and WD-repeat protein interacting with phosphoinositides (WIPI)1–4 in mammals. Mutations in the WIPI genes are a...

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Detalles Bibliográficos
Autores principales: Shimizu, Takahiro, Tamura, Norito, Nishimura, Taki, Saito, Chieko, Yamamoto, Hayashi, Mizushima, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407718/
https://www.ncbi.nlm.nih.gov/pubmed/37364041
http://dx.doi.org/10.1093/hmg/ddad096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407718/
https://www.ncbi.nlm.nih.gov/pubmed/37364041
http://dx.doi.org/10.1093/hmg/ddad096

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