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Predicting molecular mechanisms of hereditary diseases by using their tissue‐selective manifestation

How do aberrations in widely expressed genes lead to tissue‐selective hereditary diseases? Previous attempts to answer this question were limited to testing a few candidate mechanisms. To answer this question at a larger scale, we developed “Tissue Risk Assessment of Causality by Expression” (TRACE)...

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Detalles Bibliográficos
Autores principales: Simonovsky, Eyal, Sharon, Moran, Ziv, Maya, Mauer, Omry, Hekselman, Idan, Jubran, Juman, Vinogradov, Ekaterina, Argov, Chanan M, Basha, Omer, Kerber, Lior, Yogev, Yuval, Segrè, Ayellet V, Im, Hae Kyung, Birk, Ohad, Rokach, Lior, Yeger‐Lotem, Esti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407743/
https://www.ncbi.nlm.nih.gov/pubmed/37232043
http://dx.doi.org/10.15252/msb.202211407