NPC1 plays a role in the trafficking of specific cargo to melanosomes

Niemann–Pick type C1 (NPC1) protein is a multimembrane spanning protein of the lysosome limiting membrane that facilitates intracellular cholesterol and sphingolipid transport. Loss-of-function mutations in the NPC1 protein cause Niemann–Pick disease type C1, a lysosomal storage disorder characteriz...

Descripción completa

Detalles Bibliográficos
Autores principales: Rus, Alina Adriana, Militaru, Ioana V., Popa, Ioana, Munteanu, Cristian V.A., Sima, Livia Elena, Platt, Nick, Platt, Frances M., Petrescu, Ștefana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407747/
https://www.ncbi.nlm.nih.gov/pubmed/37423302
http://dx.doi.org/10.1016/j.jbc.2023.105024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407747/
https://www.ncbi.nlm.nih.gov/pubmed/37423302
http://dx.doi.org/10.1016/j.jbc.2023.105024

Ejemplares similares