An oncolytic virus–delivered TGFβ inhibitor overcomes the immunosuppressive tumor microenvironment

While checkpoint blockade immunotherapies have widespread success, they rely on a responsive immune infiltrate; as such, treatments enhancing immune infiltration and preventing immunosuppression are of critical need. We previously generated αPD-1 resistant variants of the murine HNSCC model MEER. Wh...

Descripción completa

Detalles Bibliográficos
Autores principales: DePeaux, Kristin, Rivadeneira, Dayana B., Lontos, Konstantinos, Dean, Victoria G., Gunn, William G., Watson, McLane J., Yao, Tianhong, Wilfahrt, Drew, Hinck, Cynthia, Wieteska, Lukasz, Thorne, Stephen H., Hinck, Andrew P., Delgoffe, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407786/
https://www.ncbi.nlm.nih.gov/pubmed/37552475
http://dx.doi.org/10.1084/jem.20230053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407786/
https://www.ncbi.nlm.nih.gov/pubmed/37552475
http://dx.doi.org/10.1084/jem.20230053

Ejemplares similares