Inducible HEK293 AAV packaging cell lines expressing Rep proteins

Packaging or producer cell lines for scalable recombinant adeno-associated virus (rAAV) production have been notoriously difficult to create due in part to the cytostatic nature of the Rep proteins required for AAV production. The most difficult challenge being creating AAV packaging cell lines usin...

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Detalles Bibliográficos
Autores principales: Jalšić, Lovro, Lytvyn, Viktoria, Elahi, Seyyed Mehdy, Hrapovic, Sabahudin, Nassoury, Nasha, Chahal, Parminder Singh, Gaillet, Bruno, Gilbert, Rénald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407821/
https://www.ncbi.nlm.nih.gov/pubmed/37560197
http://dx.doi.org/10.1016/j.omtm.2023.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407821/
https://www.ncbi.nlm.nih.gov/pubmed/37560197
http://dx.doi.org/10.1016/j.omtm.2023.07.002

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