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LC–MS/MS method for the quantitation of decitabine and venetoclax in rat plasma after SPE: Application to pharmacokinetic study

This study developed a novel, sensitive and selective LC-MS/MS method for the concurrent determination of DCB and VTX in rat plasma using encorafenib as internal standard (IS). To identify DCB, VTX, and IS, the positive multiple reaction monitoring (MRM) mode was used. Chromatographic separation was...

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Detalles Bibliográficos
Autores principales: Alnasser, Abdulaziz I., Hefnawy, Mohamed M., Al-Hossaini, Abdullah M., Bin Jardan, Yousef A., El-Azab, Adel S., Abdel-Aziz, Alaa M., Al-Obaid, Abdulrahman M., Al-Suwaidan, Ibrahim A., Attwa, Mohamed W., El-Gendy, Manal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407895/
https://www.ncbi.nlm.nih.gov/pubmed/37559870
http://dx.doi.org/10.1016/j.jsps.2023.06.026