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Spanlastic-laden in situ gel as a promising approach for ocular delivery of Levofloxacin: In-vitro characterization, microbiological assessment, corneal permeability and in-vivo study

The objective of this study was to encapsulate the antibacterial drug levofloxacin hemihydrate (LF) into spanlastics (SLs) followed by incorporation into gelrite in situ gel to enhance its antibacterial activity and sustain ocular delivery. A combination of Span 60 as main vesicle component and Twee...

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Detalles Bibliográficos
Autores principales: Agha, Omnia Ahmed, Girgis, Germeen N.S., El-Sokkary, Mohamed M.A., Soliman, Osama Abd El-Azeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407905/
https://www.ncbi.nlm.nih.gov/pubmed/37560488
http://dx.doi.org/10.1016/j.ijpx.2023.100201