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Lewis Acid-Catalyzed Carbonyl-Ene Reaction: Interplay between Aromaticity, Synchronicity, and Pauli Repulsion

[Image: see text] The physical factors governing the catalysis in Lewis acid-promoted carbonyl-ene reactions have been explored in detail quantum chemically. It is found that the binding of a Lewis acid to the carbonyl group directly involved in the transformation greatly accelerates the reaction by...

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Detalles Bibliográficos
Autores principales: Rodríguez, Humberto A., Cruz, Daniel A., Padrón, Juan I., Fernández, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407925/
https://www.ncbi.nlm.nih.gov/pubmed/37485981
http://dx.doi.org/10.1021/acs.joc.3c01059