d-Glucuronate and d-Glucuronate Glycal Acceptors for the Scalable Synthesis of d-GlcN-α-1,4-d-GlcA Disaccharides and Modular Assembly of Heparan Sulfate

[Image: see text] Reported herein is a scalable chemical synthesis of disaccharide building blocks for heparan sulfate (HS) oligosaccharide assembly. The use of d-glucuronate-based acceptors for dehydrative glycosylation with d-glucosamine partners is explored, enabling diastereoselective synthesis...

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Detalles Bibliográficos
Autores principales: Pongener, Imlirenla, Miller, Gavin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407932/
https://www.ncbi.nlm.nih.gov/pubmed/37458063
http://dx.doi.org/10.1021/acs.joc.3c01108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407932/
https://www.ncbi.nlm.nih.gov/pubmed/37458063
http://dx.doi.org/10.1021/acs.joc.3c01108

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