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Comparison of Quantitative Mass Spectrometric Methods for Drug Target Identification by Thermal Proteome Profiling

[Image: see text] Thermal proteome profiling (TPP) provides a powerful approach to studying proteome-wide interactions of small therapeutic molecules and their target and off-target proteins, complementing phenotypic-based drug screens. Detecting differences in thermal stability due to target engage...

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Detalles Bibliográficos
Autores principales:	George, Amy L., Sidgwick, Frances R., Watt, Jessica E., Martin, Mathew P., Trost, Matthias, Marín-Rubio, José Luis, Dueñas, Maria Emilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407934/ https://www.ncbi.nlm.nih.gov/pubmed/37439223 http://dx.doi.org/10.1021/acs.jproteome.3c00111

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